Heart attacks in your thirties. Type 2 diabetes diagnoses in your forties. Friends and classmates gone before fifty. These aren’t rare tragedies anymore; they’re becoming alarmingly common.
That stark reality is exactly what drives Zane Griggs, a veteran fitness coach who has spent nearly three decades helping people over 40 reclaim their health. When he joined Sam Tejada, CEO and founder of Liquivida®, on “A Healthy Point of View” podcast, their conversation went far beyond diet tips and workouts. Together, they explored what it really takes to stay strong as you age, why metabolic disease isn’t destiny, and how purpose plays as big a role in longevity as nutrition or exercise.
The REAL Reason You’re Tired & Gaining Fat After 40 | Zane Griggs | Ep. 84

A Personal Mission to Avoid Disease
Zane’s journey into health and wellness began long before he became a trainer. In his twenties, he watched his uncles struggle with metabolic diseases like diabetes and heart disease. Determined not to end up the same way, he made it his mission to learn everything he could about prevention.
This was the 1990s, no Google, no podcasts, no social media. Reliable information was hard to find. “We didn’t have the internet; you couldn’t just look things up,” Zane recalled. “You had to read books, ask questions, and experiment.”
Experimentation defined his early years. He tried vegetarian and vegan diets for over three years, only to find himself losing muscle and constantly hungry. It wasn’t wasted time, though. That period forced him to learn how to prepare food, balance nutrients, and understand the effects of diet on the body.
By 1998, he had become a personal trainer, not to chase bodybuilding trends, but to apply what he was learning about real health.
From Gym Bro Culture to Real-Life Health Challenges
The late 90s and early 2000s were still dominated by “bro culture” gyms filled with bodybuilders, Flex Magazines on the racks, and protein shakes everywhere. But Zane’s career took a different turn when he began working in private training studios with clients who weren’t looking for six-pack abs, but for solutions to real health problems.
He found himself helping older adults recover after surgery, navigate cancer treatments, and fight back against metabolic disease. “It wasn’t about big arms anymore,” he said. “It was about helping people live better, longer.”
That shift reshaped his philosophy. Training wasn’t just exercise; it was about addressing the whole picture: diet, lifestyle, sleep, hormones, and mindset.
Why Metabolic Health Matters After 40
Now in his mid-fifties, Zane is acutely aware of how lifestyle choices add up. Many of his peers from high school have already passed away, often from preventable diseases.
“It’s not genetics,” he insists. “A hundred years ago, people weren’t dying of diabetes and heart disease. These are modern problems, fueled by modern lifestyles.”
The main culprit? Processed foods.
Seed oils, refined sugars, and packaged meals have replaced the whole foods our grandparents grew up on. “In 1901, obesity was just 1%,” Zane explained. “Type 2 diabetes was virtually nonexistent. It skyrocketed once processed food entered the mainstream.”
His first step with every client is simple but powerful: cut ultra-processed foods as much as possible, replacing them with whole, natural options, even if the list is short. “Your health will always be better with a few whole foods than with the most ‘healthy-looking’ packaged product on the shelf.”
Data Over Guesswork
Unlike many trainers, Zane doesn’t rely on guesswork. He leans heavily on data to guide his clients. Sleep trackers like Oura or WHOOP, continuous glucose monitors, and detailed bloodwork all play a role in painting the full picture.
One of his most important tools? Fasting insulin.
“Most doctors don’t check it, but it’s one of the best markers for metabolic health. It can reveal problems years before full-blown diabetes shows up,” he explained.
He also emphasizes complete thyroid panels and hormone testing, particularly after 40, when shifts in testosterone, estrogen, or thyroid hormones can make progress harder. “If those aren’t optimized, no amount of diet or exercise will deliver the results people are hoping for.”
Smarter, Not Harder: The New Playbook for Aging Well
As Zane puts it, “You can’t train in your forties and fifties the way you did in your twenties.” Overtraining, under-eating, and crash dieting don’t just fail; they backfire. Instead, success comes from balance:
- Quality sleep to regulate hormones and hunger.
- Whole foods to reduce inflammation.
- Targeted exercise that strengthens without breaking down the body.
- And, when needed, medical tools like hormone replacement therapy (HRT).
At 48, Zane started testosterone replacement therapy after noticing his energy and motivation plummet. “I wanted to fix it naturally, but no lifestyle tweak could bring my levels back. TRT gave me my focus, creativity, and drive again.”
He’s careful to draw the line between hormone abuse and proper replacement: “It’s not about becoming a bodybuilder, it’s about optimizing health, preventing disease, and staying sharp for the second half of life.”
Tools, Not Crutches: On GLP-1 Medications
With the explosion of GLP-1 drugs, Zane takes a measured approach. “They can be effective, but they should be a tool, not a crutch,” he said.
He encourages people to use them to quiet cravings and reset habits, but always alongside lasting lifestyle changes. “The danger is becoming dependent. The goal is to build a foundation of health that lasts long after the medication is gone.”
A Bigger Movement: Make America Healthy Again
One of the most inspiring parts they discussed was around the Make America Healthy Again (MAHA) movement, which is pushing for greater awareness about food quality, seed oils, and artificial additives.
“For the first time, I’m hearing seed oils and food dyes being discussed on mainstream news and even in Congress,” Zane said. “That’s progress. Just like we eventually saw warning labels on cigarettes and alcohol, people deserve to know what’s in their food. It’s about informed consent.”
Purpose: The Real Secret to Longevity
Beyond the science, Zane believes there’s something even more important to aging well: purpose.
“Especially for men, retirement can be dangerous,” he warned. “If you lose your sense of purpose, that’s the beginning of the end. We need something to build, something to fight for, something that gives us meaning.”
For Zane, purpose comes through his work, his writing, and his family. It’s why he tells clients that health isn’t just about avoiding disease, it’s about making sure you have the strength and energy to live fully in the years you have left.
You’re Not Doomed by Genetics
Zane has a message that should give hope to anyone who feels stuck:
“You’re not genetically destined for metabolic disease. You don’t have to spend your last decades managing sickness. Start simple, eat only foods that existed 100 years ago. Get your sleep, manage stress, and track your health. You have more control than you think.”